Barbier reaction

Primary References

• Barbier, P. Compt. Rend., 1899, 128, 110.
• The original Barbier reaction combined a ketone, magnesium metal, and an alkyl halide in situ to give a substituted alcohol product.
  

• Recent Examples

  • Zhou, J-Y.; Jia, Y.; Sun, G-F.; Wu, S-H.* Synth. Commun., 1997, 27, 1899-1906.
  
  

           This is a Barbier-type coupling.